Lady A’s Charles Kelley Reveals Rare Blood Cancer Diagnosis: ‘I Feel Really Hopeful’

Kelley, 45, is opening up about his multiple myeloma diagnosis.

By

Lauren Jo Black

| Posted on

September 29, 2026

at

10:33 am

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Cassie, Charles Kelley; Photo Courtesy of Charles kelley

Lady A’s Charles Kelley, 45, has been diagnosed with a rare form of blood cancer called multiple myeloma.

The country star took to social media early Tuesday with his wife, Cassie, by his side to share the news with fans. Kelley revealed that the cancer was discovered after he sustained a “couple random rib fractures.” This prompted his doctor to have him undergo several blood tests, and they ultimately discovered the cancer through one of the last tests they ran.

Kelley is remaining positive throughout the diagnosis and says he feels hopeful about the road ahead.

Cassie, Charles Kelley; Photo Courtesy of Charles kelley
Cassie, Charles Kelley; Photo Courtesy of Charles kelley

“I’m young. I feel healthy and the treatments, I will say, have just come so far, even in the past five years, that even life expectancy is just far exceeds what it used to be. And I don’t know, I feel really hopeful. I really do,” he shared in the video message.

He explained that they have a friend who was diagnosed with multiple myeloma just weeks before him, and they have been leaning on her throughout the process.

“We have a friend going through this right now and she’s been sharing some of her journey. She’s about two months ahead of me on this. And it helped me so much watching that.”

Kelley, who began his sobriety journey in 2022, compared this health challenge to his sobriety journey and explained that being open and honest with everyone about what he is going through has been “freeing.”

He hopes to continue working as he undergoes treatment and is keeping a positive outlook on life.

“I think in sobriety, it’s all about one day at a time and that we’re not in control. And so that’s the way we’re looking at it. I mean, right now I feel great. We got a new record coming out soon with Lady A, and then we got Christmas shows. And this first six months of treatment I believe is not going to be too super invasive. I can still work. I think physically I will feel like myself. I’ll have tough days, but I want to keep working.,” he shared. “Even going out last weekend was like, after even knowing the news, it was like this is where I belong. I need to be happy and doing what I love to do and spending and sucking up as much time with my family as I can as well. But I’m hopeful. I really am. But we just want to let y’all know and I’ll try to let you in when I feel like it’s appropriate throughout the journey.”

Cassie, Charles Kelley; Photo Courtesy of Charles kelley
Cassie, Charles Kelley; Photo Courtesy of Charles kelley

According to the Cleveland Clinic, “Multiple myeloma happens when healthy plasma cells become abnormal cells that multiply and produce abnormal proteins. This can cause medical issues that can affect your bones, kidneys and blood cells.” 

Charles Kelley and his wife, Cassie, have weathered their share of challenges together, including Kelley’s battle with alcoholism. Cassie stood by his side as he sought treatment, and the couple has continued to support one another throughout their journey.

Charles Kelley and Family; Photo Courtesy of Charles Kelley
Charles Kelley and Family; Photo Courtesy of Charles Kelley

The couple has two children, Ward Charles, born February 11, 2016, and Archer Lancaster, born September 16, 2025.

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Lauren Jo Black

Written by

Lauren Jo Black

Lauren Jo Black is a longtime country music journalist, editor, host, and media personality whose work has helped shape the conversation around country music for nearly two decades. As the current Editor-in-Chief of Country Now, she has become one of the genre’s most respected voices, interviewing hundreds of country music’s biggest stars, including Dolly Parton, Garth Brooks, Reba McEntire, Shania Twain, Randy Travis, Luke Bryan, Carrie Underwood, Blake Shelton, Luke Combs, and countless others. Over the course of her career, Black’s written work and interviews have reached billions of country music fans worldwide. A 2009 graduate of the University of Central Florida, Black began her career by founding Country Music Is Love, one of country music’s earliest independent digital publications, which she later sold to a major record label in 2015 before it was rebranded as Sounds Like Nashville. She then served as the publication’s Editor-in-Chief for more than two years. Her work has also appeared in Forbes, and she previously served as the Country Music Expert for Answers.com. Widely recognized for her expertise, Black has appeared as a featured guest on The Bobby Bones Show, BobbyCast, and Scripps News Morning Rush, providing insight on country music’s biggest moments. She has also hosted Country Now Live, a concert series featuring performances from artists including Lady A, Dierks Bentley, Riley Green, Jordan Davis, Dustin Lynch, Gabby Barrett, Brett Young, Jon Pardi, Kip Moore, Chris Young, and more. The series has welcomed thousands of fans in person while reaching millions more online. In addition, she hosted Connect With Country Now, a weekly interview series featuring conversations with rising country stars. Throughout her career, Black has earned a reputation for discovering and championing artists long before they become household names. She has covered Luke Bryan since the early days of his career, beginning when he was writing songs for other artists, including Billy Currington’s No. 1 hit “Good Directions,” before stepping into the spotlight with his debut single, “All My Friends Say” and eventually becoming one of biggest names in music. She also gave Megan Moroney her first opportunity to walk a major red carpet as Country Now’s official guest correspondent at the 2022 CMA Awards. An interview she conducted in 2018 for Forbes.com with Luke Combs that inspired his multi-week No. 1 hit, “Doin’ This.” She has also hosted stages at CMA Fest, moderated an industry panel at Country Radio Seminar, and helped lead important conversations about the evolving landscape of country music media. Beyond journalism, Black has also used her platform to support charitable causes and highlight organizations making an impact. Through Country Now Live, she has helped raise awareness and support for St. Jude Children’s Research Hospital, while also advocating for animal rescue through Country Now’s Pupdate series, spotlighting organizations including MuttNation Foundation, Wags & Walks, and Proverbs 12:10 Animal Rescue. Black has been recognized as one of Country Aircheck’s Women of Influence and received the 2012 Rising Star Award from the University of Central Florida. She is a longtime member of both the Country Music Association (CMA) and the Academy of Country Music (ACM). After nearly 20 years covering country music, Lauren Jo Black has spent her career telling the stories behind the artists, songs, and moments that have shaped the genre. Her first-ever book, Country Music Forever: An A-to-Z Celebration of Icons, Songs and Stories, brings that same passion and firsthand knowledge to the page, celebrating not only the legendary artists and timeless songs that have become the soundtrack to generations of fans, but also the places, traditions, and cultural moments that have made country music one of the most beloved genres around the world.